Assay Method Information

Assay Name:  Inhibition of ALK IR Anaplastic Lymphoma Kinase Activity
Description:  To measure the activity of the N2-(2-methoxyphenyl)pyrimidine derivative represented by formula 1 of the present invention to inhibit anaplastic lymphoma kinase (ALK) activity at enzyme level, the following experiment was performed by the same manner as described in experimental example 1 except that IR (Insulin Receptor) protein was used instead of ALK WT protein.
Affinity data for this assay
 

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