| Assay Method Information | |
| | ChEMBL_1680904 (CHEMBL4031181) |
| Description: | Inhibition of human cGAS (2 to 522 residues) expressed in Sf9 insect cells assessed as reduction in cGAMP level using ISD DNA as substrate in presence of ATP and GTP incubated for 1 hr followed by Cy5-labeled cGAMP addition measured after 1 hr by fluorescence polarization assay |
| Affinity data for this assay | |
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