| Assay Method Information | |
| | ChEMBL_1656610 (CHEMBL4006080) |
| Description: | Inhibition of N-terminal 6His-tagged human DOT1L (1 to 416 residues) expressed in Escherichia coli BL21(DE3) at preincubated for 15 mins followed by [3H]-SAM addition measured after 120 mins by radioactive methylation assay |
| Affinity data for this assay | |
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