| Assay Method Information | |
| | ChEMBL_1825915 (CHEMBL4325679) |
| Description: | Inhibition of CYP3A5 in doxycycline-induced CYP3A5 overexpressing wild type human AsPC1 cells assessed as decrease in 1-hydroxymidazolam formation using midazolam as substrate pretreated with doxycycline for 24 hrs followed by incubation with compound for 24 hrs by LC-MS/MS analysis |
| Affinity data for this assay | |
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