| Assay Method Information | |
| | ChEMBL_2024829 (CHEMBL4678642) |
| Description: | Inhibition of ABCB1 in multidrug-resistant human KB-C2 cells assessed as increase in reversal of resistance to paclitaxel-induced cytotoxicity by measuring paclitaxel IC50 at 4 uM pre-incubated for 4 hrs followed by paclitaxel addition and measured after 72 hrs by MTT assay (Rvb = 1886.37 +/- 243.05 nM) |
| Affinity data for this assay | |
|---|---|
| If you find an error in this entry please send us an E-mail | |