| Assay Method Information | |
| | ChEMBL_2160671 (CHEMBL5045421) |
| Description: | Inactivation of recombinant human CYP3A4 assessed as inhibition constant using midazolam as substrate preincubated for 5 mins followed by beta-NADP addition for 15 mins and midazolam addition after 10 mins in presence of NADPH-generating system by LC-MS/MS analysis |
| Affinity data for this assay | |
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