Assay Method Information | |
| ChEMBL_1995613 (CHEMBL4629508) |
Description: | Reversal of human ABCG2-mediated multidrug resistance in HEK293/R482 cells assessed as effect on mitoxantrone-induced cytotoxicity by measuring mitoxantrone IC50 at 0.5 uM after 72 hrs by CCK8 assay (Rvb = 50.66 +/- 6.88 nM) |
Affinity data for this assay | |
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