| Details for Substrate
Amyloid-beta precursor protein without Explicit Binding Affinity Data |
| Binding Enzyme 1: | Gamma-secretase subunit APH-1A/Gamma-secretase subunit PEN-2/Nicastrin [34-709]/Presenilin-1 |
| Synonyms: |
A4
|
A4_HUMAN
|
ABPP
|
AD1
|
AICD-50
|
AICD-57
|
AICD-59
|
AID(50)
|
AID(57)
|
AID(59)
|
APP
|
APPI
|
Alzheimer disease amyloid protein
|
Amyloid beta A4 protein
|
Amyloid beta Protein
|
Amyloid beta protein (sAPPbeta)
|
Amyloid beta protein Abeta(1-42)
|
Amyloid intracellular domain 50
|
Amyloid intracellular domain 57
|
Amyloid intracellular domain 59
|
Amyloid protein (Abeta42b)
|
Amyloid β-protein (Aβ42)
|
Beta amyloid A4 protein
|
Beta-APP40
|
Beta-APP42
|
Beta-amyloid protein 40
|
Beta-amyloid protein 42
|
C31
|
C83
|
C99
|
CVAP
|
Cerebral vascular amyloid peptide
|
Gamma Secretase
|
Gamma-CTF(50)
|
Gamma-CTF(57)
|
Gamma-CTF(59)
|
Gamma-secretase
|
Gamma-secretase C-terminal fragment 50
|
Gamma-secretase C-terminal fragment 57
|
Gamma-secretase C-terminal fragment 59
|
P3(40)
|
P3(42)
|
PN-II
|
PreA4
|
Protease nexin-II
|
S-APP-alpha
|
S-APP-beta
|
Soluble APP-alpha
|
Soluble APP-beta
|
beta-Amyloid Precursor Protein (APP)
|
| Type: | Single-pass type I membrane protein |
| Topology: | n/a |
| Mol. Mass.: | 86890.41 Dalton |
| Organism: | Homo sapiens (Human) |
| Description: | P05067 |
| Residue: | 770 |
| Sequence: | MLPGLALLLLAAWTARALEVPTDGNAGLLAEPQIAMFCGRLNMHMNVQNGKWDSDPSGTKTCIDTKEGILQYCQEVYPELQITNVVEANQPVTIQNWCKRGRKQCKTHPHFVIPYRCLVGEFVSDALLVPDKCKFLHQERMDVCETHLHWHTVAKETCSEKSTNLHDYGMLLPCGIDKFRGVEFVCCPLAEESDNVDSADAEEDDSDVWWGGADTDYADGSEDKVVEVAEEEEVAEVEEEEADDDEDDEDGDEVEEEAEEPYEEATERTTSIATTTTTTTESVEEVVREVCSEQAETGPCRAMISRWYFDVTEGKCAPFFYGGCGGNRNNFDTEEYCMAVCGSAMSQSLLKTTQEPLARDPVKLPTTAASTPDAVDKYLETPGDENEHAHFQKAKERLEAKHRERMSQVMREWEEAERQAKNLPKADKKAVIQHFQEKVESLEQEAANERQQLVETHMARVEAMLNDRRRLALENYITALQAVPPRPRHVFNMLKKYVRAEQKDRQHTLKHFEHVRMVDPKKAAQIRSQVMTHLRVIYERMNQSLSLLYNVPAVAEEIQDEVDELLQKEQNYSDDVLANMISEPRISYGNDALMPSLTETKTTVELLPVNGEFSLDDLQPWHSFGADSVPANTENEVEPVDARPAADRGLTTRPGSGLTNIKTEEISEVKMDAEFRHDSGYEVHHQKLVFFAEDVGSNKGAIIGLMVGGVVIATVIVITLVMLKKKQYTSIHHGVVEVDAAVTPEERHLSKMQQNGYENPTYKFFEQMQN |
| |
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