Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 1C5W
TargetUrokinase-type plasminogen activator(Human)
Axys Pharmaceutical

LigandPNGBDBM14169(CA-01 | [amino(4-iodo-1-benzothiophen-2-yl)methyli...)
Affinity DataKi:  210nM ΔG°:  -37.7kJ/molepH: 7.4 T: 2°CAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/6/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetUrokinase-type plasminogen activator(Human)
Axys Pharmaceutical

LigandPNGBDBM14169(CA-01 | [amino(4-iodo-1-benzothiophen-2-yl)methyli...)
Affinity DataKi:  250nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM14169(CA-01 | [amino(4-iodo-1-benzothiophen-2-yl)methyli...)
Affinity DataKi:  1.70E+3nMAssay Description:Each enzyme was assayed with a set of different concentrations of each inhibitor. After addition of the appropriate substrate, the rate of hydrolysis...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/24/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)