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Found
1
Enz. Inhib. hit(s) for PDB:
1H08
Target
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1
(Human)
Astrazeneca
Ligand
BDBM7627
(5-bromo-2-N-{4-[3-(dimethylamino)-2-hydroxypropoxy...)
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Affinity Data
IC50: 300nM
Assay Description:
The kinase activity was assayed using an in vitro scintillation proximity assay (SPA) for measuring incorporation of [gamma-33P] ATP into GST-Rb.
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Target Info
PDB
UniProtKB/SwissProt
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Ligand Info
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
2/13/2006
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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