Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 1JLQ
TargetGag-Pol polyprotein [588-1027]/[588-1147](Human immunodeficiency virus type 1)
Glaxosmithkline

LigandPNGBDBM1802(2-amino-6-[(3,5-dimethylbenzene)sulfonyl]benzonitr...)
Affinity DataIC50: 7nMAssay Description:The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/20/2004
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
University of Perugia

Curated by ChEMBL
LigandPNGBDBM1802(2-amino-6-[(3,5-dimethylbenzene)sulfonyl]benzonitr...)
Affinity DataIC50: 7.10nMAssay Description:Inhibitory concentration against Reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/23/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM1802(2-amino-6-[(3,5-dimethylbenzene)sulfonyl]benzonitr...)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/1/2020
Entry Details Article
PDB3D3D Structure (crystal)
TargetReverse transcriptase(Human immunodeficiency virus type 1)TBA
LigandPNGBDBM1802(2-amino-6-[(3,5-dimethylbenzene)sulfonyl]benzonitr...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of HIV1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/27/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)