Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 1MQ5
TargetCoagulation factor X(Human)
Berlex Biosciences

LigandPNGBDBM17085(thiophene-containing non-amidine inhibitor, 31 | 3...)
Affinity DataKi:  0.760nM ΔG°:  -51.5kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/8/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Berlex Biosciences

LigandPNGBDBM17085(thiophene-containing non-amidine inhibitor, 31 | 3...)
Affinity DataKi:  1nM ΔG°:  -50.9kJ/molepH: 7.5 T: 2°CAssay Description:The enzyme activities were determined kinetically as the initial rate of cleavage of a peptide p-nitroanilide. Km for enzyme and substrate was determ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)