Report error Found 11 Enz. Inhib. hit(s) for PDB: 1NAV
Affinity DataIC50: 25nM EC50: 1.70nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataEC50: 4.5nMAssay Description:Agonist activity at human thyroid hormone receptor alpha expressed in CV1 cells by TRE-luciferase assayMore data for this Ligand-Target Pair
Affinity DataEC50: 5nMAssay Description:Agonist activity at recombinant His6-tagged THR-alpha (unknown origin) expressed in Escherichia coli BL21(DE3) co-expressing RXR preincubated for 30 ...More data for this Ligand-Target Pair
Affinity DataKi: 7.18nMAssay Description:Binding affinity to TRalpha1More data for this Ligand-Target Pair
Affinity DataKi: 7.18nMAssay Description:Displacement of [125I]T3 from recombinant thyroid hormone receptor alpha expressed in sf9 cells by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataKi: 7.79nMAssay Description:Displacement of [125I]3,5,3'-triiodo-L-thyronine from His-tagged human recombinant TRalpha1 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 25nM EC50: 11nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. EC50 is the concentration of compound required to ...More data for this Ligand-Target Pair
Affinity DataIC50: 25nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
Affinity DataIC50: 25nMpH: 7.0 T: 2°CAssay Description:IC50 is the concentration of each compound required to inhibit 50% binding of 125I-T3 to hTRalpha. More data for this Ligand-Target Pair
Affinity DataIC50: 25nMAssay Description:Inhibitory concentration against cloned human thyroid hormone receptor alpha 1More data for this Ligand-Target Pair
Affinity DataIC50: 25.1nMAssay Description:Inhibition of thyroid hormone receptor alphaMore data for this Ligand-Target Pair