Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 1NO6
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13952(2-(Naphthalen-1-yloxalylamino)benzoic Acid | 2-(na...)
Affinity DataKd:  2.60E+4nMAssay Description:Dissociation constant for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM13952(2-(Naphthalen-1-yloxalylamino)benzoic Acid | 2-(na...)
Affinity DataKi:  2.40E+4nM ΔG°:  -26.1kJ/mole Kd:  2.60E+4nMpH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/27/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM13952(2-(Naphthalen-1-yloxalylamino)benzoic Acid | 2-(na...)
Affinity DataKi:  3.90E+4nM ΔG°:  -24.9kJ/molepH: 7.5 T: 2°CAssay Description:The phosphatase activity resulted in the formation of the colored product p-nitrophenol, which was continuously monitored at 405 nm every 30 s for 15...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13952(2-(Naphthalen-1-yloxalylamino)benzoic Acid | 2-(na...)
Affinity DataKi:  3.90E+4nMAssay Description:Binding affinity for Protein-tyrosine phosphatase 1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein phosphatase non-receptor type 1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM13952(2-(Naphthalen-1-yloxalylamino)benzoic Acid | 2-(na...)
Affinity DataKi:  1.58E+5nMAssay Description:Inhibition of PTP1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)