Compile Data Set for Download or QSAR
Report error Found 6 Enz. Inhib. hit(s) for PDB: 1Q41
TargetGlycogen synthase kinase-3 beta(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50166289(CHEBI:43645 | CHEMBL216543)
Affinity DataIC50: 22nMAssay Description:Inhibition of GSK3beta (unknown origin) assessed as decrease in tau phosphorylation at Ser214 residue incubated for 30 mins by Western blot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Pig)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50166289(CHEBI:43645 | CHEMBL216543)
Affinity DataIC50: 22nMAssay Description:Inhibition of porcine brain GSK-3alpha/beta incubated for 30 mins in presence of [33p]-gamma ATP by scintillation counter analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlycogen synthase kinase-3 beta(Rat)
National Institute of Pharmaceutical Education and Research (NIPER)

Curated by ChEMBL
LigandPNGBDBM50166289(CHEBI:43645 | CHEMBL216543)
Affinity DataIC50: 22nMAssay Description:Inhibition of recombinant recombinant rat GSK3beta using GS-1 peptide as substrate in presence of [gamma-32P]ATP measured after 30 mins incubation by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlycogen synthase kinase-3 beta(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50166289(CHEBI:43645 | CHEMBL216543)
Affinity DataIC50: 22nMAssay Description:Inhibition of GSK-3beta (unknown origin) expressed in Sf21 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlycogen synthase kinase-3 beta(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50166289(CHEBI:43645 | CHEMBL216543)
Affinity DataIC50: 190nMAssay Description:Inhibition of GSK3beta (unknown origin) in presence of ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2023
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetGlycogen synthase kinase-3 beta(Human)
Zunyi Medical University

Curated by ChEMBL
LigandPNGBDBM50166289(CHEBI:43645 | CHEMBL216543)
Affinity DataIC50: 200nMAssay Description:Inhibition of GSK3beta (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/18/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)