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Found
2
Enz. Inhib. hit(s) for PDB:
1S9J
Target
Dual specificity mitogen-activated protein kinase kinase 1
(Human)
Genuv
US Patent
Ligand
BDBM520651
(US11147816, PD318088 | US11701360, PD318088)
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Affinity Data
IC50: 1.40nM
Assay Description:
The IC50 for MEK1 and 2 can be measured by methods in references such as [Yamaguchi et al. (2011) International Journal of Oncology 39:23-31].
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
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Ligand Info
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PC cid
PC sid
PDB
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In Depth
Date in BDB:
3/12/2022
Entry Details
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US Patent
PDB
3D Structure (crystal)
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Target
Dual specificity mitogen-activated protein kinase kinase 1/2
(Human)
Genuv
US Patent
Ligand
BDBM520651
(US11147816, PD318088 | US11701360, PD318088)
Copy SMILES
Copy InChI
Affinity Data
IC50: 1.40nM
Assay Description:
TBD
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
Purchase
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
8/18/2023
Entry Details
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US Patent
PDB
3D Structure (crystal)
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