Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 1U9V
TargetCathepsin K(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19746(CHEMBL363847 | Purine lead structure, 1 | 6-(cyclo...)
Affinity DataIC50: 6nMAssay Description:The substrate hydrolysis with or without inhibitor was monitored at an excitation wavelength of 360nm and an emission wavelength of 460 nm on a fluor...More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/5/2008
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCathepsin K(Human)
Novartis Pharmaceuticals

LigandPNGBDBM19746(CHEMBL363847 | Purine lead structure, 1 | 6-(cyclo...)
Affinity DataIC50: 6nMAssay Description:Inhibitory concentration against recombinant human cathepsin K by using Z-Phe-Arg-AMC as synthetic substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)