Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 2BDJ
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50314074(2,6,9-Trisubstitute purine, 6 (AP23464) | CHEMBL10...)
Affinity DataIC50: 0.450nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/29/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50314074(2,6,9-Trisubstitute purine, 6 (AP23464) | CHEMBL10...)
Affinity DataIC50: 0.450nMAssay Description:Inhibition of SrcMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/28/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50314074(2,6,9-Trisubstitute purine, 6 (AP23464) | CHEMBL10...)
Affinity DataIC50: 0.450nMpH: 7.4 T: 2°CAssay Description:Inhibition of human Src kinase activity by ARIAD compounds were measured in a homogeneous time-resolved fluorescence resonance energy transfer (TR-FR...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/17/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50314074(2,6,9-Trisubstitute purine, 6 (AP23464) | CHEMBL10...)
Affinity DataIC50: 0.450nMAssay Description:Inhibition of 6x-His-tagged human Src kinase domain (T250 to L536 residues) expressed in Sf9 cells incubated for 2 hrs in presence of biotinylated cd...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Nerviano Medical Sciences

Curated by ChEMBL
LigandPNGBDBM50314074(2,6,9-Trisubstitute purine, 6 (AP23464) | CHEMBL10...)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of SRCMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/7/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)