Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 2BQW
TargetCoagulation factor X(Human)
Aventis Pharma Deutschland

LigandPNGBDBM12400(1-{[(4-chlorophenyl)carbamoyl]methyl}-N-[1-(propan...)
Affinity DataKi:  3nM ΔG°:  -48.6kJ/molepH: 7.8 T: 2°CAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/27/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Aventis Pharma Deutschland

LigandPNGBDBM12400(1-{[(4-chlorophenyl)carbamoyl]methyl}-N-[1-(propan...)
Affinity DataKi:  3nMAssay Description:The inhibitory effect of test compound for human fXa was determined by using the chromogenic substrates S-2765. The hydrolysis rates of chromogenic s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/11/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Aventis Pharma Deutschland

LigandPNGBDBM12400(1-{[(4-chlorophenyl)carbamoyl]methyl}-N-[1-(propan...)
Affinity DataKi:  3nMAssay Description:Inhibition of human fXa assessed as inhibition constant using Cbz-D-Arg-Gly-L-Arg-pNA as substrate preincubated for 30 mins followed by substrate add...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2023
Entry Details
PubMedPDB3D3D Structure (crystal)