Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 2FM5
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM14360((R)-(-)-3-{2-[(3-cyclopropyloxy-4-difluromethoxy)p...)
Affinity DataIC50: 40nMpH: 7.5 T: 2°CAssay Description:PDE4 catalytic activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using PDE-SPA kit (Amersham International). [3H]-AMP was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4D(Human)
University of North Carolina At Chapel Hill

LigandPNGBDBM14360((R)-(-)-3-{2-[(3-cyclopropyloxy-4-difluromethoxy)p...)
Affinity DataIC50: 43nMpH: 7.5 T: 2°CAssay Description:PDE4 catalytic activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using PDE-SPA kit (Amersham International). [3H]-AMP was c...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/26/2007
Entry Details Article
PubMedPDB3D3D Structure (crystal)