Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 2PAX
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Konstanz

LigandPNGBDBM27498(4-Amino-1,8-naphthalimide | 10-amino-3-azatricyclo...)
Affinity DataIC50: 22nMpH: 7.8 T: 2°CAssay Description:The enzymatic reaction of the recombinant PARP was quantified by SPA. Radioactivity incorporated from [3H]NAD+ into PAR, and then being captured by P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/9/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Konstanz

LigandPNGBDBM27498(4-Amino-1,8-naphthalimide | 10-amino-3-azatricyclo...)
Affinity DataIC50: 26nMAssay Description:Inhibitory activity against human PARP1 expressed in PC12 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Konstanz

LigandPNGBDBM27498(4-Amino-1,8-naphthalimide | 10-amino-3-azatricyclo...)
Affinity DataIC50: 180nMAssay Description:The compound was tested for poly(ADP-ribose)-polymerase (PARP) inhibitionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPoly [ADP-ribose] polymerase 1(Human)
University of Konstanz

LigandPNGBDBM27498(4-Amino-1,8-naphthalimide | 10-amino-3-azatricyclo...)
Affinity DataIC50: 180nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/11/2025
Entry Details
PubMedPDB3D3D Structure (crystal)