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Found
2
Enz. Inhib. hit(s) for PDB:
2VX1
Target
Ephrin type-B receptor 4
(Human)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50293238
(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
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Affinity Data
IC50: 220nM
Assay Description:
Inhibition of EphB4
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
DrugBank
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
8/25/2010
Entry Details
Article
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PubMed
PDB
3D Structure (crystal)
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Target
Ephrin type-B receptor 4
(Human)
Astrazeneca
Curated by
ChEMBL
Ligand
BDBM50293238
(3-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimi...)
Copy SMILES
Copy InChI
Affinity Data
IC50: 900nM
Assay Description:
Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISA
More data for this Ligand-Target Pair
Target Info
PDB
KEGG
UniProtKB/SwissProt
GoogleScholar
Ligand Info
CHEMBL
DrugBank
PC cid
PC sid
PDB
Similars
In Depth
Date in BDB:
8/25/2010
Entry Details
Article
Copy BDB DOI
PubMed
PDB
3D Structure (crystal)
Copy reaction URL