Report error Found 7 Enz. Inhib. hit(s) for PDB: 2XJX
Affinity DataIC50: 13nMAssay Description:Displacement of FITC-geldanamycin from N-terminal HSP90alpha (unknown origin) after 30 mins by fluorescence polarization competitive binding assayMore data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 14nMAssay Description:Inhibition of FITC-labeled geldanamycin binding to recombinant HSP90alpha (unknown origin) after 1 hr by fluorescence polarization assayMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of FITC-geldanamycin binding to recombinant human full-length C-terminal His-tagged HSP90alpha N-terminal domain (1 to 732 residues) expre...More data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 22nMAssay Description:Inhibition of FITC-geldanamycin binding to human His-tagged HSP90alpha N-terminal domain (1 to 236 residues) expressed in Escherichia coli BL21star (...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:Displacement of FITC-geldanamycin from HSP90 (unknown origin) after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
TargetHeat shock protein HSP 90-alpha/90-beta(Human)
China Pharmaceutical University
Curated by ChEMBL
China Pharmaceutical University
Curated by ChEMBL
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant full-length HSP90 ATPase activity N-terminal domain (9 to 236 residues) (unknown origin) expressed in Escherichia coli BL21...More data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of full-length HSP90 (unknown origin) expressed in Escherichia coli assessed as inhibition of ATPase activity after 3 hrs by spectrophotom...More data for this Ligand-Target Pair