Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 3ARN
LigandPNGBDBM101888(CHEMBL1234485 | US8530490, 158)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human dUTPase-mediated formation of [5-3H]dUMP expressed in Escherichia coli BL21 (DE3) after 15 mins by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM101888(CHEMBL1234485 | US8530490, 158)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of human dUTPase assessed as production of [5-3H]dUMP from [5-3H]dUTP after 15 mins measured by HPLC analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/8/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM101888(CHEMBL1234485 | US8530490, 158)
Affinity DataEC50:  5.10E+3nMAssay Description:Inhibition of human dUTPase-mediated cell proliferation in HeLa S3 cells assessed as compound concentration required to reduce 50% of 1 uM of FdUrd T...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM101888(CHEMBL1234485 | US8530490, 158)
Affinity DataIC50: 9.48E+3nMAssay Description:The inhibitory activity of the compound against human dUTPase was determined by measuring the production of [5-3H]deoxyuridine monophosphate from [5-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/4/2013
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)