Report error Found 2 Enz. Inhib. hit(s) for PDB: 3B92
TargetDisintegrin and metalloproteinase domain-containing protein 17 [215-477,S266A,N452Q](Human)
Vertex Pharmaceuticals
Vertex Pharmaceuticals
Affinity DataKi: 10nM ΔG°: -45.2kJ/molepH: 7.5 T: 2°CAssay Description:The compounds were tested for TACE inhibition using fluorescence resonance energy transfer (FRET) assay. TACE catalyzed cleavage of the substrate pep...More data for this Ligand-Target Pair
3D Structure (crystal)TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
University of Athens
Curated by ChEMBL
University of Athens
Curated by ChEMBL