Compile Data Set for Download or QSAR
Report error Found 7 Enz. Inhib. hit(s) for PDB: 3C13
TargetCasein kinase II subunit alpha/beta(Human)
Instituto Universitario De Bio-Org£Nica Antonio Gonz£Lez (Cibican)

Curated by ChEMBL
LigandPNGBDBM11318(1,3,8-trihydroxy-6-methylanthra-9,10-quinone | CHE...)
Affinity DataIC50: 580nMAssay Description:Inhibition of human CK2-alpha/beta expressed in Escherichia coli BL21(DE3) using RRRDDDSDDD peptide as substrate after 15 mins by capillary electroph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM11318(1,3,8-trihydroxy-6-methylanthra-9,10-quinone | CHE...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha(Human)
Osaka Prefecture University

Curated by ChEMBL
LigandPNGBDBM11318(1,3,8-trihydroxy-6-methylanthra-9,10-quinone | CHE...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of GST-fused human recombinant CK2alpha expressed in Escherichia coli HMS174 (DE3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
1/11/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha(Human)
Osaka Prefecture University

Curated by ChEMBL
LigandPNGBDBM11318(1,3,8-trihydroxy-6-methylanthra-9,10-quinone | CHE...)
Affinity DataKi:  1.50E+3nMAssay Description:Inhibition of CK2alpha (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM11318(1,3,8-trihydroxy-6-methylanthra-9,10-quinone | CHE...)
Affinity DataKi:  1.85E+3nMAssay Description:Binding affinity to CK2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha(Human)
Osaka Prefecture University

Curated by ChEMBL
LigandPNGBDBM11318(1,3,8-trihydroxy-6-methylanthra-9,10-quinone | CHE...)
Affinity DataKi:  1.85E+3nM ΔG°:  -32.4kJ/mole IC50: 890nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM11318(1,3,8-trihydroxy-6-methylanthra-9,10-quinone | CHE...)
Affinity DataKi:  1.90E+3nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2022
Entry Details Article
PubMedPDB3D3D Structure (crystal)