Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 3CBD
TargetBifunctional cytochrome P450/NADPH--P450 reductase(Bacillus megaterium)
University of Manchester

LigandPNGBDBM212439(N-palmitoylglycine (NPG))
Affinity DataKd:  82nMpH: 7.0Assay Description:Dissociation constants (Kd values) for binding of the substrates N-palmitoylglycine (NPG) and omeprazole (OMP) to WT and mutant BM3 heme domains were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBifunctional cytochrome P450/NADPH--P450 reductase [A82F](Bacillus megaterium)
University of Manchester

LigandPNGBDBM212439(N-palmitoylglycine (NPG))
Affinity DataKd:  297nMpH: 7.0Assay Description:Dissociation constants (Kd values) for binding of the substrates N-palmitoylglycine (NPG) and omeprazole (OMP) to WT and mutant BM3 heme domains were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBifunctional cytochrome P450/NADPH--P450 reductase [F87V](Bacillus megaterium)
University of Manchester

LigandPNGBDBM212439(N-palmitoylglycine (NPG))
Affinity DataKd:  204nMpH: 7.0Assay Description:Dissociation constants (Kd values) for binding of the substrates N-palmitoylglycine (NPG) and omeprazole (OMP) to WT and mutant BM3 heme domains were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBifunctional cytochrome P450/NADPH--P450 reductase [A82F,F87V](Bacillus megaterium)
University of Manchester

LigandPNGBDBM212439(N-palmitoylglycine (NPG))
Affinity DataKd:  4nMpH: 7.0Assay Description:Dissociation constants (Kd values) for binding of the substrates N-palmitoylglycine (NPG) and omeprazole (OMP) to WT and mutant BM3 heme domains were...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)