Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 3CS8
TargetPeroxisome proliferator-activated receptor alpha/delta/gamma(Human)
Southwest University

Curated by ChEMBL
LigandPNGBDBM50030474(US9562012, rosiglitazone | CHEBI:50122 | Avandamet...)
Affinity DataEC50:  120nMAssay Description:Activation of PPAR in human HepG2 cells after 24 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor alpha/delta/gamma(Human)
Southwest University

Curated by ChEMBL
LigandPNGBDBM50030474(US9562012, rosiglitazone | CHEBI:50122 | Avandamet...)
Affinity DataEC50:  1.60E+3nMAssay Description:Transactivation of PPAR transfected in human HepG2 cells after 20 hrs by PPAR-luciferase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetPeroxisome proliferator-activated receptor gamma(Mouse)
Institute of Chinese Materia Medica

Curated by ChEMBL
LigandPNGBDBM50030474(US9562012, rosiglitazone | CHEBI:50122 | Avandamet...)
Affinity DataEC50:  30nMAssay Description:Agonist activity at mouse PPARgamma expressed in HEK293 cells co-expressing with Gal4 reporter vector after 24 hrs by dual-luciferase reporter assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)