Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 3E30
LigandPNGBDBM31423(ethylenediamine scaffold, 4)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of Rap1A geranylgeranylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM31423(ethylenediamine scaffold, 4)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of H-Ras farnesylation expressed in mouse NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM31423(ethylenediamine scaffold, 4)
Affinity DataIC50: 3.70E+3nMpH: 7.7 T: 2°CAssay Description:In vitro inhibition assay of human PFT was done by measuring the incorporation of [3H] FPP (Amersham Biosciences, Piscataway, NJ) into wild type H-Ra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/13/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM31423(ethylenediamine scaffold, 4)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of human farnesyltransferase assessed as incorporation of [3H]FPP into H-Ras-CVLSMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM31423(ethylenediamine scaffold, 4)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human geranylgeranyltransferase-1 assessed as incorporation of [3H]GGPP into H-Ras-CVLLMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/12/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)