Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 3E67
TargetNitric oxide synthase, inducible(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091800(4-METHYLPYRIDIN-2-AMINE, 6 | 4-METHYLPYRIDIN-2-AMI...)
Affinity DataIC50: 10nMAssay Description:In vitro inhibition of human inducible nitric oxide synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, inducible(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091800(4-METHYLPYRIDIN-2-AMINE, 6 | 4-METHYLPYRIDIN-2-AMI...)
Affinity DataIC50: 120nMpH: 7.0 T: 2°CAssay Description:Nitric oxide formation from NOS was monitored by the hemoglobin capture assay. The assay was initiated by addition of enzyme and was monitored at 401...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, inducible(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091800(4-METHYLPYRIDIN-2-AMINE, 6 | 4-METHYLPYRIDIN-2-AMI...)
Affinity DataIC50: 120nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetNitric oxide synthase, inducible(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50091800(4-METHYLPYRIDIN-2-AMINE, 6 | 4-METHYLPYRIDIN-2-AMI...)
Affinity DataIC50: 170nMAssay Description:Inhibitory activity against inducible nitric oxide synthase (iNOS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)