Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 3GYF
TargetDihydrofolate reductase(Human)
Duquesne University

LigandPNGBDBM33395(Z-isomer | 2,4-diaminofuro[2,3-d]pyrimidine, 1b)
Affinity DataIC50: 1.90E+3nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Mouse)
Duquesne University

LigandPNGBDBM33395(Z-isomer | 2,4-diaminofuro[2,3-d]pyrimidine, 1b)
Affinity DataIC50: 3.90E+3nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Rat)
Duquesne University

LigandPNGBDBM33395(Z-isomer | 2,4-diaminofuro[2,3-d]pyrimidine, 1b)
Affinity DataIC50: 1.02E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)