Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 3K3J
LigandPNGBDBM84801(PF-00416121)
Affinity DataIC50: 2.40E+3nMpH: 7.5 T: 2°CAssay Description:Binding of inhibitors to unactivated p38a that leads to decreasedphosphorylation of p38alpha by MKK6 was determined by measuringthe activated p38alph...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetMitogen-activated protein kinase 11/12/13/14(Human)
University of Zagreb

Curated by ChEMBL
LigandPNGBDBM84801(PF-00416121)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of MAPK p38 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/17/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM84801(PF-00416121)
Affinity DataIC50: 1.25E+4nMpH: 7.5 T: 2°CAssay Description:Inhibition of active p38a MAP kinase by inhibitors was determinedusing a p38a cascade activity assay. A 30-lL reaction mixture wasprepared containing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/10/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)