Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 3KJS
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma cruzi)
University of Alabama

Curated by ChEMBL
LigandPNGBDBM50320792(Ethyl4-(5-[(2,4-diamino-6-quinazolinyl)methyl]amin...)
Affinity DataIC50: 23.8nMAssay Description:Inhibition of Trypanosoma cruzi DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma cruzi)
University of Alabama

Curated by ChEMBL
LigandPNGBDBM50320792(Ethyl4-(5-[(2,4-diamino-6-quinazolinyl)methyl]amin...)
Affinity DataKi:  1.30nMAssay Description:Inhibition of Trypanosoma cruzi DHFR by spectrophotometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetBifunctional dihydrofolate reductase-thymidylate synthase(Trypanosoma cruzi)
University of Alabama

Curated by ChEMBL
LigandPNGBDBM50320792(Ethyl4-(5-[(2,4-diamino-6-quinazolinyl)methyl]amin...)
Affinity DataKi:  5.68nMAssay Description:Inhibition of Trypanosoma cruzi DHFR by Lineweaver-Burke plotMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/20/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)