Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 3KL6
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50317098(TAK-442 | 1-(1-{(2S)-3-[(6-chloronaphthalen-2-yl)s...)
Affinity DataKi:  1.80nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50317098(TAK-442 | 1-(1-{(2S)-3-[(6-chloronaphthalen-2-yl)s...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of human factor 10a using S2222 as substrate after 10 mins by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50317098(TAK-442 | 1-(1-{(2S)-3-[(6-chloronaphthalen-2-yl)s...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of factor 10aMore data for this Ligand-Target Pair
In Depth
Date in BDB:
1/2/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCoagulation factor X(Human)
Bristol-Myers Squibb

Curated by ChEMBL
LigandPNGBDBM50317098(TAK-442 | 1-(1-{(2S)-3-[(6-chloronaphthalen-2-yl)s...)
Affinity DataIC50: 3.5nMAssay Description:Inhibition of human factor 10a assessed as p-nitroanilide release using S2765 as substrate by chromogenic assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/19/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)