Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 3LBK
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50436047(CHEMBL1233798)
Affinity DataKi:  916nMAssay Description:Binding affinity to human MDM2 assessed as dissociation constant by FP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50436047(CHEMBL1233798)
Affinity DataKi:  916nMAssay Description:Binding affinity to human MDM2 by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/15/2016
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50436047(CHEMBL1233798)
Affinity DataKi:  916nMAssay Description:Displacement of fluorescent P4 peptide from recombinant human MDM2 (18 to 125) expressed in Escherichia coli BL21(DE3) RIL expression system after 30...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/9/2015
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50436047(CHEMBL1233798)
Affinity DataKi:  920nMAssay Description:Binding affinity to MDM2 (unknown origin) expressed in Escherichia coli BL21(DE3) after 30 mins by fluorescence polarization assay in presence of P4 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetE3 ubiquitin-protein ligase Mdm2(Human)
University of Chinese Academy of Sciences

Curated by ChEMBL
LigandPNGBDBM50436047(CHEMBL1233798)
Affinity DataKi:  920nMAssay Description:Competition binding affinity to MDM2 (unknown origin) using p53 mimicking peptide TSFAEYWNLLSP after 30 mins by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/4/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)