Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 3N5T
TargetNitric oxide synthase, endothelial(Human)
Northwestern University

US Patent
LigandPNGBDBM50341682(NOS Inhibitor, 3j | 6,6'-(pyridine-3,5-diyldiethan...)
Affinity DataKi:  2.68E+3nMAssay Description:The NOSs isoform assays involved subjecting 3-8 to an oxyhemoglobin NO capture assay using a Biotek Gen5 microplate reader. IC50 values for each comp...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/16/2020
Entry Details
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TargetNitric oxide synthase, endothelial(Human)
Northwestern University

US Patent
LigandPNGBDBM50341682(NOS Inhibitor, 3j | 6,6'-(pyridine-3,5-diyldiethan...)
Affinity DataKi:  2.68E+3nMAssay Description:Inhibition assay using nitric oxide synthases.More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2013
Entry Details Article
PubMed
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

US Patent
LigandPNGBDBM50341682(NOS Inhibitor, 3j | 6,6'-(pyridine-3,5-diyldiethan...)
Affinity DataKi:  2.68E+3nMAssay Description:Enzyme inhibition was evaluated by measuring NO production with the hemoglobin capture assay, which was performed with purified NOSs in 96-well plate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/18/2021
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetNitric oxide synthase, endothelial(Bovine)
Northwestern University

US Patent
LigandPNGBDBM50341682(NOS Inhibitor, 3j | 6,6'-(pyridine-3,5-diyldiethan...)
Affinity DataKi:  2.68E+3nMAssay Description:Inhibition of bovine recombinant eNOS expressed in Escherichia coli by UV-vis spectrometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/3/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)