Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 3NXO
TargetDihydrofolate reductase(Mouse)
Duquesne University

LigandPNGBDBM33397(E/Z ratio=3:1 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 4.14E+3nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Human)
Duquesne University

LigandPNGBDBM33397(E/Z ratio=3:1 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 6.35E+3nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetDihydrofolate reductase(Rat)
Duquesne University

LigandPNGBDBM33397(E/Z ratio=3:1 | 2,4-diaminofuro[2,3-d]pyrimidine, ...)
Affinity DataIC50: 1.19E+4nMAssay Description:Cells used were tumor cell lines naturally expressing high levels of tyrosine kinases. Expression levels at the RNA level were derived from the NCI D...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/6/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)