Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 3OYS
TargetCarbonic anhydrase 2(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM35733(sulfonamide deriv., 7a)
Affinity DataKi:  9nMAssay Description:Inhibition of human carbonic anhydrase 2 preincubated with compound for 15 mins by carbon dioxide hydration assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM35733(sulfonamide deriv., 7a)
Affinity DataKi:  107nMAssay Description:Inhibition of human recombinant carbonic anhydrase 2 by stopped flow CO2 hydration methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/5/2011
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCarbonic anhydrase 2(Human)
The Hebrew University of Jerusalem

Curated by ChEMBL
LigandPNGBDBM35733(sulfonamide deriv., 7a)
Affinity DataKi:  107nM ΔG°:  -39.8kJ/molepH: 7.4 T: 2°CAssay Description:An SX.18MV-R Applied Photophysics (Oxford, UK) stopped-flow instrument has been used to assay the catalytic/inhibition of various CA isozymes. Phenol...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/9/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)