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Report error Found 6 Enz. Inhib. hit(s) for PDB: 3PE2
TargetCasein kinase II subunit alpha 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM165355(US9062043, Table 20b, Compound 15 | US9062043, Tab...)
Affinity DataKi:  0.420nMAssay Description:Binding affinity to CK2 (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM165355(US9062043, Table 20b, Compound 15 | US9062043, Tab...)
Affinity DataIC50: 2.30nMAssay Description:Inhibition of CK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/22/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM165355(US9062043, Table 20b, Compound 15 | US9062043, Tab...)
Affinity DataIC50: 6nMpH: 7.2Assay Description:Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2016
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM165355(US9062043, Table 20b, Compound 15 | US9062043, Tab...)
Affinity DataIC50: 6nMAssay Description:Test compounds in aqueous solution were added at a volume of 10 microliters, to a reaction mixture comprising 10 microliters Assay Dilution Buffer (A...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/31/2023
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM165355(US9062043, Table 20b, Compound 15 | US9062043, Tab...)
Affinity DataIC50: 98nMpH: 7.4Assay Description:The human leukemia Jurkat T-cell line was maintained in RPMI 1640 (Cambrex) supplemented with 10% fetal calf serum and 50 ng/ml Geutamycin. Before tr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/22/2016
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)
TargetCasein kinase II subunit alpha(Human)
Senhwa Biosciences

US Patent
LigandPNGBDBM165355(US9062043, Table 20b, Compound 15 | US9062043, Tab...)
Affinity DataKi:  420nMAssay Description:Inhibition of CK2alpha (unknown origin) using RRRADDSDDDDD as substrate in presence of [gamma33P]-ATP by autoradiographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/19/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)