Report error Found 37 Enz. Inhib. hit(s) for PDB: 3QMO
Affinity DataIC50: 1nMAssay Description:The compound was evaluated for prostaglandin E2 inhibition using recombinant Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 2nMAssay Description:Inhibitory activity against murine Prostaglandin G/H synthase 2.More data for this Ligand-Target Pair
Affinity DataIC50: 7nMAssay Description:Inhibition of COX-2 in mouse RAW264.7 cells assessed as decrease in LPS-induced PGE2 production treated prior to LPS challenge by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 10nMAssay Description:Tested for inhibition against Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:IC50 value against Prostaglandin G/H synthase 2 of murine J774A.1 cell lineMore data for this Ligand-Target Pair
Affinity DataIC50: 22nMAssay Description:IC50 value was determined against Prostaglandin G/H synthase 2 of J7744A.1 cell lines.More data for this Ligand-Target Pair
Affinity DataIC50: 50nMAssay Description:Inhibition of COX2-mediated PGE2 production in LPS-stimulated mouse RAW264.7 cells by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 90nMAssay Description:In vitro inhibitory activity against Prostaglandin G/H synthase 2 (COX-2) in humanMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:In vitro inhibition of prostaglandin G/H synthase 2 (COX-2).More data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:In vitro inhibitory activity against inducible form of human recombinant cyclooxygenase (COX-2)More data for this Ligand-Target Pair
Affinity DataIC50: 120nMAssay Description:Inhibition of the human Prostaglandin G/H synthase 2 was determined by thin-layer chromatography assayMore data for this Ligand-Target Pair
Affinity DataIC50: 150nMAssay Description:Inhibition of COX2 by microplate readerMore data for this Ligand-Target Pair
Affinity DataIC50: 160nMAssay Description:Inhibition of COX2 by scintillation proximity assayMore data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:IC50 against recombinant human Prostaglandin G/H synthase 2More data for this Ligand-Target Pair
Affinity DataIC50: 190nMAssay Description:Inhibition of recombinant human prostaglandin G/H synthase 2 (COX-2)More data for this Ligand-Target Pair
Affinity DataIC50: 260nMAssay Description:Inhibition of COX2 (unknown origin) using arachidonic acid as substrate preincubated for 20 mins followed by substrate addition measured at 1 sec int...More data for this Ligand-Target Pair
Affinity DataIC50: 610nMAssay Description:Inhibition of COX2 in human whole blood assessed as effect on LPS-stimulated PGE2 productionMore data for this Ligand-Target Pair
Affinity DataIC50: 810nMAssay Description:Inhibition of COX2 in mouse RAW264.7 cells by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant COX2 assessed as inhibition of PGF2alpha production from PGH2 by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of recombinant human COX2 by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant COX-2 assessed as decrease in PGH2 production using arachidonic acid as substrate treated with enzyme for 10 mins pri...More data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of human recombinant COX2 in cell-free system by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of sheep placental COX2 assessed as PGE2 production by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant COX2 assessed as prostaglandin F2alpha levelMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of recombinant human COX2 assessed as decrease in PGE2 release after 10 mins by ELISAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10E+3nMpH: 8.0 T: 2°CAssay Description:Reaction mixtures were prepared in 100 mM Tris HCl buffer, pH 8.0 containing 1 µM heme and COX-1 or COX-2 and preincubated for 10 min in a waterbath ...More data for this Ligand-Target Pair
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of human recombinant COX-2 using PGH2 as substrate incubated for 10 mins prior to arachidonic acid addition measured after 2 mins by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of sheep placental cotyledens COX2 assessed as PGE2 level by EIAMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:Inhibition of COX2 in sheep placental vesicle by enzyme immunoassayMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibitory concentration required against COX-2 activity in intact human monocytesMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of COX2-catalyzed prostaglandin biosynthesis after 10 mins of preincubationMore data for this Ligand-Target Pair
Affinity DataIC50: 5.30E+4nMAssay Description:Inhibition of sheep placental cotyledons COX2 assessed as PGE2 production preincubated for 10 minsMore data for this Ligand-Target Pair
Affinity DataIC50: 7.32E+4nMAssay Description:Inhibition of sheep COX2 by spectrophotometryMore data for this Ligand-Target Pair