Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 3SRV
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419247(CHEMBL1835071 | US8470835, 1)
Affinity DataIC50: 32nMAssay Description:Inhibition of human full-length recombinant 6His-SYK assessed as phosphorylation of Biotin-AAAEEIYGEI substrate after 60 mins by by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase SYK(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50419247(CHEMBL1835071 | US8470835, 1)
Affinity DataIC50: 40nMpH: 7.4 T: 2°CAssay Description:Syk was pre-activated at room temperature for 30 mins in the presence of 16.6 mM MgCl2, 8.3 mM ATP and then diluted to 4 nM in 40 mM Hepes pH 7.4, 0....More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/24/2013
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)