Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 3TN8
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Palacky University

LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 350nMT: 2°CAssay Description:In vitro CDK assay using purified enzyme, was incubated at 30 °C with substrate, and test compounds in the presence of ATP/ [gamma-32P] ATP. 32P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2006
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 9(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM50352019(CHEMBL1823556)
Affinity DataIC50: 350nMAssay Description:Inhibition of CDK9 by [33P]gamma-ATP incorporation assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Palacky University

LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataKi:  350nMAssay Description:Inhibition of CDK9/Cyclin T (1 to 330 amino acid residues) (unknown origin) by differential scanning fluorimetry assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetCyclin-dependent kinase 9(Human)
Palack£

Curated by ChEMBL
LigandPNGBDBM12028(4-[(E)-2-(3,5-diamino-1H-pyrazol-4-yl)diazen-1-yl]...)
Affinity DataIC50: 350nMAssay Description:Cyclin-dependent kinase selectivity was evaluated using CDK1-cyclin B, CDK2-cyclin E, CDK4-cyclin D1, CDK7-cyclin H, and CDK9-cyclin T1.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/5/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)