Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) for PDB: 3TUD
TargetTyrosine-protein kinase SYK(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM92626(Pyrido analog, 3)
Affinity DataIC50: 2nMAssay Description:Inhibition of SYK (unknown origin) using FAM-labeled peptide as substrate preincubated for 10 mins followed by substrate addition measured after 25 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2019
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetTyrosine-protein kinase SYK(Human)
Second Military Medical University

Curated by ChEMBL
LigandPNGBDBM92626(Pyrido analog, 3)
Affinity DataIC50: 2.10nMpH: 7.4 T: 2°CAssay Description:A Lance TR-FRET assay (Perkin Elmer) was used to measure and compare the potency of compounds against Syk kinase domain.More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/20/2012
Entry Details Article
PubMedPDB3D3D Structure (crystal)