Compile Data Set for Download or QSAR
Report error Found 3 Enz. Inhib. hit(s) for PDB: 3TV4
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50484702(CHEMBL1945020)
Affinity DataIC50: 110nMAssay Description:Inhibition of full length human B-Raf V600E mutant expressed in baculovirus infected insect cells assessed as [gamma-33P]incorporation into MEK after...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50484702(CHEMBL1945020)
Affinity DataIC50: 310nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human MALME-3M cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSerine/threonine-protein kinase B-raf(Human)
Array Biopharma

Curated by ChEMBL
LigandPNGBDBM50484702(CHEMBL1945020)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of B-Raf V600E mutant-mediated Erk phosphorylation in human A375 cells after 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2020
Entry Details Article
PubMedPDB3D3D Structure (crystal)