Report error Found 5 Enz. Inhib. hit(s) for PDB: 3TVX
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Human)
Hokuriku University
Curated by ChEMBL
Hokuriku University
Curated by ChEMBL
Affinity DataKi: 3.77E+4nMAssay Description:Inhibition of cyclic AMP-phosphodiesterase ( PDE) in the supernatant of tracheal muscle homogenateMore data for this Ligand-Target Pair
3D Structure (crystal)TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4B(Human)
Jagiellonian University
Curated by ChEMBL
Jagiellonian University
Curated by ChEMBL
Affinity DataIC50: 9.00E+4nMAssay Description:Inhibition of human GST-tagged PDE4B expressed in baculovirus infected Sf9 insect cells using cAMP as substrate after 10 mins by PDE-Glo Phosphodiest...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Vrije Universiteit Amsterdam
Curated by ChEMBL
Vrije Universiteit Amsterdam
Curated by ChEMBL
Affinity DataIC50: 1.68E+5nMAssay Description:Inhibition of human N-terminal His6-tagged PDE4A10 catalytic domain expressed in Escherichia coli BL21(DE3) RIL cells using 3',5'-cAMP as substrate b...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Vrije Universiteit Amsterdam
Curated by ChEMBL
Vrije Universiteit Amsterdam
Curated by ChEMBL
Affinity DataIC50: 1.68E+5nMpH: 7.5 T: 2°CAssay Description:Phosphodiesterase 4A (PDE4A) was assayed using an Sf9-expressed GST-fusion, and activity was monitored by hydrolysis of [3H]cAMP to [3H]AMP using the...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A(Human)
Vrije Universiteit Amsterdam
Curated by ChEMBL
Vrije Universiteit Amsterdam
Curated by ChEMBL
Affinity DataIC50: 1.68E+5nMAssay Description:Inhibition of human N-terminal His6-tagged PDE4A10 catalytic domain expressed in Escherichia coli BL21(DE3) RIL cells using 3',5'-cAMP as substrate b...More data for this Ligand-Target Pair