Report error Found 5 Enz. Inhib. hit(s) for PDB: 3UFY
TargetAldo-keto reductase family 1 member C3(Human)
The Trustees of The University of Pennsylvania
US Patent
The Trustees of The University of Pennsylvania
US Patent
Affinity DataIC50: 50nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Human)
The Trustees of The University of Pennsylvania
US Patent
The Trustees of The University of Pennsylvania
US Patent
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant AKR1C3 using S-tetralol as substrate assessed as reduction in NADP+-dependent S-tetralol oxidation preincubated for 1...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C3(Human)
The Trustees of The University of Pennsylvania
US Patent
The Trustees of The University of Pennsylvania
US Patent
Affinity DataIC50: 180nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Human)
The Trustees of The University of Pennsylvania
US Patent
The Trustees of The University of Pennsylvania
US Patent
Affinity DataIC50: 2.75E+3nMAssay Description:the inhibitory potency of the individual compounds against the AKR1C isoforms was determined by monitoring the NADP+ dependent oxidation of S-tetralo...More data for this Ligand-Target Pair
TargetAldo-keto reductase family 1 member C2(Human)
The Trustees of The University of Pennsylvania
US Patent
The Trustees of The University of Pennsylvania
US Patent
Affinity DataIC50: 2.75E+3nMAssay Description:Inhibition of human recombinant AKR1C2 using S-tetralol as substrate assessed as reduction in NADP+-dependent S-tetralol oxidation preincubated for 1...More data for this Ligand-Target Pair

3D Structure (crystal)