Compile Data Set for Download or QSAR
Report error Found 9 Enz. Inhib. hit(s) for PDB: 3VJC
TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50051873((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of rat liver squalene synthase by liqiud scintillation countingMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2010
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSqualene synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50051873((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: 5nMAssay Description:Inhibition of Candida albicans squalene synthase(SQS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetSqualene synthase(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50051873((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: 5nMAssay Description:In vitro inhibitory activity of compound was measured against Candida squalene synthase(SQS) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article
PDB3D3D Structure (crystal)
TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50051873((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory activity against Squalene synthase from ratsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50051873((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: 12nMAssay Description:Inhibition of rat liver squalene synthase(SQS)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50051873((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibition of rat squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50051873((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: 12nMAssay Description:Inhibitory concentration against mammalian Squalene synthaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50051873((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory concentration against squalene synthase from male rat liver microsomesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/19/2010
Entry Details Article
PDB3D3D Structure (crystal)
TargetSqualene synthase(Rat)
TBA

Curated by ChEMBL
LigandPNGBDBM50051873((1S,3S,4S,5R,6R,7R)-1-((4S,5R)-4-Acetoxy-5-methyl-...)
Affinity DataIC50: 12nMAssay Description:In vitro inhibitory activity measured against rat squalene synthase(SQS) enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2012
Entry Details Article
PDB3D3D Structure (crystal)