Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 3VYF
TargetRenin(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50402224(CHEMBL2204739)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of recombinant human renin using Arg-Glu(EDANS)-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(DABCYL)-Arg as substrate incubated for 10 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Human)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50402224(CHEMBL2204739)
Affinity DataIC50: 1.60nMAssay Description:Inhibition of trypsin-activated human recombinant renin using (Arg-Glu(EDANS)-Ile-His-Pro-Phe-His-Leu-Val-Ile-His-Thr-Lys(DABCYL)-Arg) as substrate i...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Crab-eating macaque)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50402224(CHEMBL2204739)
Affinity DataIC50: 10nMAssay Description:Inhibition of renin in cynomolgus monkey plasma after 60 mins by competitive radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetRenin(Crab-eating macaque)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50402224(CHEMBL2204739)
Affinity DataIC50: 10nMAssay Description:Inhibition of cynomolgus monkey plasma renin assessed as angiotensin 1 level after 60 mins by competitive radioimmunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)