Compile Data Set for Download or QSAR
Report error Found 5 Enz. Inhib. hit(s) for PDB: 3WAV
LigandPNGBDBM103961(Monosubstituted aryl-Me ATX inhibitor 5 | Disubsti...)
Affinity DataIC50: 180nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM103961(Monosubstituted aryl-Me ATX inhibitor 5 | Disubsti...)
Affinity DataIC50: 180nMAssay Description:Inhibition of ATX (unknown origin) expressed in human HEK293 cells using TG-mTMP as substrate after 2 hrs by fluorescence based plate reader assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetAutotaxin(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM103961(Monosubstituted aryl-Me ATX inhibitor 5 | Disubsti...)
Affinity DataIC50: 180nMAssay Description:Inhibition of human recombinant ATXMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM103961(Monosubstituted aryl-Me ATX inhibitor 5 | Disubsti...)
Affinity DataIC50: 240nMAssay Description:Inhibitory activities of hit compounds towards ENPP1-5 were calculated using pNP-TMP, and the inhibitory activities of hit compounds towards ENPP6 an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM103961(Monosubstituted aryl-Me ATX inhibitor 5 | Disubsti...)
Affinity DataIC50: 640nMAssay Description:Inhibitory activities of hit compounds towards ENPP1-5 were calculated using pNP-TMP, and the inhibitory activities of hit compounds towards ENPP6 an...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2014
Entry Details Article
PubMedPDB3D3D Structure (crystal)