Compile Data Set for Download or QSAR
Report error Found 4 Enz. Inhib. hit(s) for PDB: 3WIG
LigandPNGBDBM50010462(CHEMBL3264002 | CHEBI:78825 | US11147816, RO512676...)
Affinity DataIC50: 160nMAssay Description:The IC50 for MEK1 and 2 can be measured by methods in references such as [Yamaguchi et al. (2011) International Journal of Oncology 39:23-31].More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2022
Entry Details
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PDB3D3D Structure (crystal)
LigandPNGBDBM50010462(CHEMBL3264002 | CHEBI:78825 | US11147816, RO512676...)
Affinity DataIC50: 160nMAssay Description:TBDMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
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PDB3D3D Structure (crystal)
LigandPNGBDBM50010462(CHEMBL3264002 | CHEBI:78825 | US11147816, RO512676...)
Affinity DataIC50: 160nMAssay Description:Inhibition of MEK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMedPDB3D3D Structure (crystal)
LigandPNGBDBM50010462(CHEMBL3264002 | CHEBI:78825 | US11147816, RO512676...)
Affinity DataIC50: 292nMAssay Description:The test compound, CRAF (Thermo Fisher Scientific Inc.), MEK1 (Thermo Fisher Scientific Inc.) and ERK2 (Carna Biosciences, Inc.) were mixed in ATP-co...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/15/2023
Entry Details
Go to US Patent
PDB3D3D Structure (crystal)